In Study RA-III, the types and frequencies of adverse reactions in the second year open-label extension were similar to those observed in the one-year double-blind portion. I had a very itchy rash basically all In Ps patients who were on HUMIRA monotherapy and subsequently withdrawn from the treatment, the rate of antibodies to adalimumab after retreatment was similar to the rate observed prior to withdrawal. A biopsy showed a spongiotic dermatitis with eosinophils, therefore he was referred to an allergist. Metabolic And Nutritional Disorders: